What does the existing research say?
The most recent report, “The effect of human chorionic gonadotropin (hCG) in the treatment of obesity by means of the Simeons therapy: a criteria-based meta-analysis,” was written in 1995 by Lijeseen, Theeuwen, Assendelft, and Van Der Wal.
They concluded “…there is no scientific evidence that hCG causes weight-loss, a redistribution of fat, staves off hunger or induces a feeling of well-being. Therefore, the use of hCG should be regarded as an inappropriate therapy for weight reduction, particularly because hCG is obtained from the urine of pregnant women who donate their urine idealistically in the belief that it will be used to treat an entirely different condition, namely infertility.” They were surprised by the lack of research after 1977 and found that the small amount of research they reviewed was lacking in methodological quality.
Their summary, based on the conclusion of only 12 studies, are true. HCG is not an appetite suppressant, it doesn’t burn calories, it’s not an anti-depressant, and it doesn’t move fat around. If it did, all pregnant women would feel cheery, wouldn’t be hungry and would lose fat.
As for whether or not hCG is appropriate for weight loss? Not without the very low calorie protocol. HCG is only useful in burning fat and increasing metabolism if the 500 calorie protocol is followed.